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Author Topic: case study on nicotine poisoning  (Read 272 times)
taz3cat
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« on: January 20, 2010, 09:09:08 PM »

That was a lot of nicotine to main line and it was a full impact hit in an instant. The women walked into the hospital 7 hours later. That must have been horrible 7 hours before she could get herself to the hospital. I am wondering (only) how much you would have to drink to equal  the same dose of nicotine or the very same reaction.

DO NOT DO THIS


Hum Exp Toxicol. 2010 Jan 12. [Epub ahead of print]

Nicotine poisoning due to intravenous injection of cigarette soakage.

Hagiya K, Mizutani T, Yasuda S, Kawano S.
epartment of Emergency and Critical Care Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan.

A 27-year-old female nurse intravenously injected 5 mL of cigarette soakage solution that contained approximately 5.7 mg nicotine, in a suicidal attempt. Clinical manifestations consisted of nausea, palpitation, abdominal pain, repeated vomiting, and diarrhea. She remained fully conscious during this episode. About 7 hours later, she visited emergency department on foot and received fluid infusion for dehydration. She fully recovered at night of the day. This is the first documented report of acute nicotine poisoning due to intravenous injection of cigarette soakage in humans. Signs and symptoms appeared immediately after the injection, but this case seemed to be relatively mild in terms of clinical manifestation. The elimination half-life of nicotine seems to be short, that is, less than 1 hour. Therefore, if initial treatment is appropriate and the patient can survive acute phase of nicotine poisoning, prognosis is good.

http://www.ncbi.nlm.nih.gov/pubmed/20068013?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum&ordinalpos=33
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